Focus on Chikungunya pathophysiology in human and animal models.

  title={Focus on Chikungunya pathophysiology in human and animal models.},
  author={Th{\'e}r{\'e}se Couderc and Marc Lecuit},
  journal={Microbes and infection},
  volume={11 14-15},
Chikungunya virus (CHIKV) is an arbovirus responsible for acute febrile arthralgia. It re-emerged abruptly in 2005 and caused a massive outbreak in the Indian Ocean region, and then extended to Asia. Here we review the pathophysiology of CHIKV infection, based on human and mouse studies, and also present prospects for prevention and therapy of this infection. Our results are discussed in the light of the current knowledge regarding other arthritogenic Alphaviruses. 
Related Discussions
This paper has been referenced on Twitter 12 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 24 extracted citations

Chikungunya: A Potentially Emerging Epidemic?

PLoS neglected tropical diseases • 2010
View 10 Excerpts
Highly Influenced

Arboviruses and the eye

International journal of retina and vitreous • 2017
View 3 Excerpts


Publications referenced by this paper.
Showing 1-10 of 71 references

Severe neonatal encephalopathy and haemorrhagic fever as a complication of maternofetal transmission of Chikungunya virus

P. Gérardin, M. Carbonnier, +11 authors P.-Y. Robillard
PLoS Med. 5 • 2008
View 9 Excerpts
Highly Influenced

Characterization of Reemerging Chikungunya Virus

PLoS pathogens • 2007
View 4 Excerpts
Highly Influenced

How did chikungunya reach the Indian Ocean?

The Lancet. Infectious diseases • 2006
View 4 Excerpts
Highly Influenced

Chikungunya : no longer a third world disease

Lecuit / Microbes and Infection • 2009

Prophylaxis and therapy for Chikungunya virus infection.

The Journal of infectious diseases • 2009
View 2 Excerpts

Similar Papers

Loading similar papers…