Focus: Human African trypanosomiasis

@article{Kioy2004FocusHA,
  title={Focus: Human African trypanosomiasis},
  author={Deborah W Kioy and Jean Jannin and Nina Mattock},
  journal={Nature Reviews Microbiology},
  year={2004},
  volume={2},
  pages={186-187}
}
BACKGROUND Causative agents. Human African trypanosomiasis (HAT), also known as sleeping sickness, is caused by single-celled parasites, Trypanosoma brucei, which are transmitted to humans by infected tsetse flies. Two sub-species of T. brucei cause different forms of the disease. T. b. gambiense causes chronic infection, whereas T. b. rhodesiense generally causes a more acute infection. The parasites first develop in the blood, lymph and peripheral organs (stage 1), then spread to the central… 
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