Focal cortical dysplasia of Taylor's balloon cell type: mutational analysis of the TSC1 gene indicates a pathogenic relationship to tuberous sclerosis.

@article{Becker2002FocalCD,
  title={Focal cortical dysplasia of Taylor's balloon cell type: mutational analysis of the TSC1 gene indicates a pathogenic relationship to tuberous sclerosis.},
  author={Albert J. Becker and Horst Urbach and Bjoern Scheffler and Thomas Baden and Sabine Normann and Rainer Lahl and Heinz Wolfgang Pannek and Ingrid E. B. Tuxhorn and Christian Erich Elger and Johannes Schramm and Otmar Dieter Wiestler and Ingmar Bl{\"u}mcke},
  journal={Annals of neurology},
  year={2002},
  volume={52 1},
  pages={29-37}
}
Focal cortical dysplasia (FCD) is characterized by a localized malformation of the neocortex and underlying white matter. Balloon cells, similar to those observed in tuberous sclerosis, are present in many cases (FCD(bc)). In these patients, a hyperintense funnel-shaped subcortical lesion tapering toward the lateral ventricle was the characteristic finding on fluid-attenuated inversion recovery magnetic resonance imaging scans. Surgical lesionectomy results in complete seizure relief. Although… CONTINUE READING

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