Focal adhesion kinase.

  title={Focal adhesion kinase.},
  author={Ian C. Zachary},
  journal={The international journal of biochemistry & cell biology},
  volume={29 7},
  • Ian C. Zachary
  • Published 1997 in
    The international journal of biochemistry & cell…
Focal adhesion kinase (FAK) is a member of a growing family of non-receptor protein tyrosine kinases. Though originally identified as a putative substrate for the oncogenic tyrosine kinase pp60v-src, it is now well-established that FAK tyrosine phosphorylation is induced by adhesion of cell surface integrins to extracellular matrix and by a variety of other extracellular factors including the ligands for receptor tyrosine kinases and for seven transmembrane domain G-protein-coupled receptors… CONTINUE READING


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