Focal adhesion kinase modulates radial glia-dependent neuronal migration through connexin-26.

@article{Valiente2011FocalAK,
  title={Focal adhesion kinase modulates radial glia-dependent neuronal migration through connexin-26.},
  author={Manuel Valiente and Gabriele Ciceri and Beatriz Rico and Oscar Mar{\'i}n},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2011},
  volume={31 32},
  pages={11678-91}
}
Focal adhesion kinase (FAK) is an intracellular kinase and scaffold protein that regulates migration in many different cellular contexts but whose function in neuronal migration remains controversial. Here, we have analyzed the function of FAK in two populations of neurons with very distinct migratory behaviors: cortical interneurons, which migrate tangentially and independently of radial glia; and pyramidal cells, which undergo glial-dependent migration. We found that FAK is dispensable for… CONTINUE READING

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docytosis regulates cell soma translocation and the distribution of adhesion proteins in migrating neurons

  • T Shu, R Ayala, Nguyen, Z Xie, JG Gleeson, LH Tsai
  • PLoS One
  • 2004
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