Focal adhesion kinase functions downstream of Sema3A signaling during axonal remodeling.


Axon refinement is a necessary event for sculpting the final wiring of neural circuits. Although some factors have been identified that cause axonal arbor remodeling, the molecular pathways transducing these extracellular signals to adhesion disassembly and the cytoskeleton are poorly understood. Here we show that conditional ablation of Focal adhesion… (More)
DOI: 10.1016/j.mcn.2010.02.001


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