Focal Transient Cerebral Ischemia in the Squirrel Monkey EFFECT ON BRAIN ADENOSINE TRIPHOSPHATE AND LACTATE LEVELS WITH ELECTROCORTICOGRAPHIC AND PATHOLOGIC

Abstract

Cerebral adenosine triphosphate and lactate concentrations were measured in the squirrel monkey (Saimiri sciureus) before, during, and at selected times after various periods of middle cerebral artery occlusion. The gradual decrease in ATP to 55, 35, and 20%, of normal and the increase in lactate to 7, 8, and 10 times normal after 2, 3, and 4 hours of… (More)

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