Focal Reduction in Cardiac 123I-Metaiodobenzylguanidine Uptake in Patients With Anderson-Fabry Disease.

@article{Yamamoto2016FocalRI,
  title={Focal Reduction in Cardiac 123I-Metaiodobenzylguanidine Uptake in Patients With Anderson-Fabry Disease.},
  author={Saori Yamamoto and Hideaki Suzuki and K Sugimura and Shunsuke Tatebe and Tatsuo Aoki and Masanobu Miura and Nobuhiro Yaoita and Haruka Sato and Katuya Kozu and Hideki Ota and Kentaro Takanami and K Takase and Hiroaki Shimokawa},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2016},
  volume={80 12},
  pages={2550-2551}
}
BACKGROUND It remains to be elucidated whether cardiac sympathetic nervous activity is impaired in patients with Anderson-Fabry disease (AFD).Methods and Results:We performed 123I-meta-iodobenzylguanidine (MIBG) scintigraphy and gadolinium-enhanced cardiovascular magnetic resonance (CMR) in 5 AFD patients. MIBG uptake in the inferolateral wall, where wall thinning and delayed enhancement were noted on CMR, was significantly lower compared with the anteroseptal wall. The localized reduction in… CONTINUE READING
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