Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis

@article{Miller2017FocalCH,
  title={Focal CA3 hippocampal subfield atrophy following LGI1 VGKC-complex antibody limbic encephalitis},
  author={Thomas D. Miller and Trevor T.-J. Chong and Anne M Aimola Davies and Tammy W. C. Ng and Michael R. Johnson and Sarosh R. Irani and Angela Vincent and Masud Husain and Saiju Jacob and Paul Maddison and Christopher Kennard and Penny A. Gowland and Clive R. Rosenthal},
  journal={Brain},
  year={2017},
  volume={140},
  pages={1212 - 1219}
}
Autoantibodies linked with voltage-gated potassium channel (VGKC)-complex antibody-mediated limbic encephalitis (LE) bind to hippocampal subfields. Miller et al. report that chronic LGI1 antibody VGKC-complex LE is associated with focal CA3 atrophy on 7.0-Tesla neuroimaging and autobiographical episodic amnesia. The results point to antibody-mediated pathogenicity and CA3-mediated impairment of episodic memory. 

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