Foals are interferon gamma-deficient at birth.

  title={Foals are interferon gamma-deficient at birth.},
  author={Cormac C Breathnach and T Sturgill-Wright and Jackie L Stiltner and Amanda A. Adams and David P. Lunn and David W. Horohov},
  journal={Veterinary immunology and immunopathology},
  volume={112 3-4},
The increased vulnerability of foals to specific pathogens such as Rhodococcus equi is believed to reflect an innate immunodeficiency, the nature of which remains poorly understood. Previous studies have demonstrated that neonates of many species fail to mount potent Th1 responses. The current research investigates the ability of circulating and pulmonary lymphocytes of developing foals to produce interferon gamma (IFNgamma). Peripheral blood mononuclear cells (PBMC) were prepared from up to 10… CONTINUE READING
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