Fmoc-amino acid chlorides in solid phase synthesis of opioid peptides.

@article{Sivanandaiah1992FmocaminoAC,
  title={Fmoc-amino acid chlorides in solid phase synthesis of opioid peptides.},
  author={K. M. Sivanandaiah and V. S. S. Suresh Babu and C Renukeshwar},
  journal={International journal of peptide and protein research},
  year={1992},
  volume={39 3},
  pages={201-6}
}
Fmoc-amino acid chlorides were employed in the solid phase synthesis of the opioid peptides [Leu]enkephalin, [Leu]enkephalin amide, and dermorphin. The conventional polystyrene-based Merrifield resin or Wang's resin served as solid support. A binary salt of either triethylamine or diisopropylethylamine in the presence of 1-hydroxybenzotriazole or pivalic… CONTINUE READING