Fluxes and accumulation of tetracyclines by human blood cells.

  title={Fluxes and accumulation of tetracyclines by human blood cells.},
  author={W. Gabler},
  journal={Research communications in chemical pathology and pharmacology},
  volume={72 1},
  • W. Gabler
  • Published 1991 in
    Research communications in chemical pathology and…
Tetracyclines (Tc's) have anti-inflammatory properties unrelated to their antibiotic activities. Their anti-inflammatory property, in part, results from the ability of members of this family of antibiotic to inhibit neutrophil functions. There are marked differences in the ability of different Tc's to suppress neutrophils which may relate to their ability to cross the plasma membrane. To gain insight into the mechanism of Tc inhibition of neutrophils and the reason for the differences in… CONTINUE READING


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