Flux or speed? Examining speckle contrast imaging of vascular flows.

@article{Kazmi2015FluxOS,
  title={Flux or speed? Examining speckle contrast imaging of vascular flows.},
  author={Syed Mohammad Shams Kazmi and Ehssan Faraji and Mitchell A. Davis and Yu-Yen Huang and Xiaojing John Zhang and Andrew K. Dunn},
  journal={Biomedical optics express},
  year={2015},
  volume={6 7},
  pages={2588-608}
}
Speckle contrast imaging enables rapid mapping of relative blood flow distributions using camera detection of back-scattered laser light. However, speckle derived flow measures deviate from direct measurements of erythrocyte speeds by 47 ± 15% (n = 13 mice) in vessels of various calibers. Alternatively, deviations with estimates of volumetric flux are on average 91 ± 43%. We highlight and attempt to alleviate this discrepancy by accounting for the effects of multiple dynamic scattering with… CONTINUE READING

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