Flux balance analysis for ethylene formation in genetically engineered Saccharomyces cerevisiae.

@article{Larsson2011FluxBA,
  title={Flux balance analysis for ethylene formation in genetically engineered Saccharomyces cerevisiae.},
  author={Christer Larsson and Jacky L. Snoep and Joakim Norbeck and Eva Albers},
  journal={IET systems biology},
  year={2011},
  volume={5 4},
  pages={245-51}
}
Biosynthesis of ethylene (ethene) is mainly performed by plants and some bacteria and fungi, via two distinct metabolic routes. Plants use two steps, starting with S-adenosylmethionine, while the ethylene-forming microbes perform an oxygen dependent reaction using 2-oxoglutarate and arginine. Introduction of these systems into Saccharomyces cerevisiae was studied in silico. The reactions were added to a metabolic network of yeast and flux over the two networks was optimised for maximal ethylene… CONTINUE READING

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