Fluvoxamine for children and adolescents with obsessive-compulsive disorder: a randomized, controlled, multicenter trial.
@article{Riddle2001FluvoxamineFC,
title={Fluvoxamine for children and adolescents with obsessive-compulsive disorder: a randomized, controlled, multicenter trial.},
author={Mark A. Riddle and Elizabeth A. Reeve and Jose A. Yaryura-Tobias and H M Yang and James L. Claghorn and Gary R. Gaffney and John H. Greist and D E Holland and Brian J. Mcconville and Teresa A Pigott and John T. Walkup},
journal={Journal of the American Academy of Child and Adolescent Psychiatry},
year={2001},
volume={40 2},
pages={
222-9
}
}OBJECTIVE
To determine the safety and efficacy of fluvoxamine for the treatment of children and adolescents with obsessive-compulsive disorder (OCD) with a double-blind, placebo-controlled, multicenter study.
METHOD
Subjects, aged 8 to 17 years, meeting DSM-III-R criteria for OCD were recruited from July 1991 to August 1994. After a 7- to 14-day single-blind, placebo washout/screening period, subjects were randomly assigned to fluvoxamine 50 to 200 mg/day or placebo for 10 weeks. Subjects who…
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