Fluvoxamine Treatment and D2 Receptors: a Pet Study on OCD Drug-Naïve Patients

  title={Fluvoxamine Treatment and D2 Receptors: a Pet Study on OCD Drug-Na{\"i}ve Patients},
  author={Rosa Maria Moresco and Lucia Pietra and Marta Henin and Andrea Panzacchi and Marco Locatelli and Lorena Bonaldi and Assunta Carpinelli and Clara Gobbo and Laura Bellodi and Daniela Perani and Ferruccio Fazio},
Changes in D2 receptors during antidepressant therapy have been reported in patients with major depressive disorder using PET/SPET. The aim of this study was to evaluate modifications in D2 receptors that might occur in patients affected by obsessive-compulsive disorder (OCD) during serotonin reuptake sites inhibitors (SSRIs). To this purpose, we measured the in vivo binding of [11C]raclopride ([11C]Rac)in the brain of a group of OCD naïve patients before and after the repeated administration… CONTINUE READING


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