Fluvoxamine—A new serotonin re-uptake inhibitor: First clinical and psychometric experiences in depressed patients

@article{Saletu1977FluvoxamineANS,
  title={Fluvoxamine—A new serotonin re-uptake inhibitor: First clinical and psychometric experiences in depressed patients},
  author={Bernd Saletu and M. Schjerve and Josef Gr{\"u}nberger and Hans Schanda and Olaf Arnold},
  journal={Journal of Neural Transmission},
  year={1977},
  volume={41},
  pages={17-36}
}
The clinical efficacy of fluvoxamine (DU 23000)-the first selective serotonin re-uptake inhibitor of the new class of 2-aminoethyloximethers of aralkylketones was investigated in endormorphous depressed patients during 5 weeks treatment with mean daily dosages of approximately 150 mg DU 23000. A marked and statistically significant improvement of the overall and detailed psychopathology was noted by means of the Global Clinical Impression and Hamilton Rating Scale as early as in the first week… CONTINUE READING

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