Fluvastatin improves lipid abnormalities in patients with moderate to advanced chronic renal insufficiency.

@article{Samuelsson2002FluvastatinIL,
  title={Fluvastatin improves lipid abnormalities in patients with moderate to advanced chronic renal insufficiency.},
  author={Ola Samuelsson and P. O. Attman and Carolyn Knight-Gibson and Henrik Mulec and Lars Weiss and Petar Alaupovic},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={2002},
  volume={39 1},
  pages={67-75}
}
Chronic renal insufficiency is characterized by specific abnormalities in lipoprotein metabolism, affecting both apolipoprotein A (apo A)- and apo B-containing lipoproteins. To evaluate the effects of fluvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, on renal dyslipoproteinemia, we performed a randomized, double-blind, placebo-controlled, two-way, period cross-over study. Study patients were administered fluvastatin, 40 mg/d, or placebo during 8 weeks in… CONTINUE READING

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