Flutamide in the treatment of hirsutism

@article{Motta1991FlutamideIT,
  title={Flutamide in the treatment of hirsutism},
  author={Tiziano Motta and G C Maggi and Maria Teresa Perra and E Azzolari and S Casazza and Alberto D'Alberton},
  journal={International Journal of Gynecology \& Obstetrics},
  year={1991},
  volume={36}
}
The Use of Antiandrogen of Hirsutism Flutamide in the Treatment
TLDR
Clinical examinations revealed that after six months of the therapy the dose of flutamide had caused a significant alleviation of hirsutism and this continued during the following months.
The use of antiandrogen flutamide in the treatment of hirsutism.
TLDR
Clinical examinations revealed that after six months of the therapy the dose of flutamide had caused a significant alleviation of hirsutism and this continued during the following months.
Treatment of hirsutism by finasteride and flutamide in women with polycystic ovary syndrome.
TLDR
Finasteride and flutamide are effective in the treatment of hirsutism in patients with polycystic ovary syndrome and both antiandrogens significantly reduced the Ferriman-Gallwey score and hair diameter.
Antiandrogen and hormonal treatment of acne.
  • J. C. Shaw
  • Medicine, Biology
    Dermatologic clinics
  • 1996
UPDATE ON IDIOPATHIC HIRSUTISM: DIAGNOSIS AND TREATMENT
  • C. Erem
  • Medicine, Biology
    Acta clinica Belgica
  • 2013
TLDR
Combination treatment of IH, including androgen suppression, peripheral androgen blockade and cosmetic methods is most effective.
Very low dose of flutamide in the treatment of hyperandrogenism
TLDR
Very low dose of flutamide was successful and safe and in the treatment of hyperandrogenism in adolescence and an almost recovery of acne (98% of patients) with better results of those obtained in control group.
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Flutamide is a new nonsteroidal antiandrogen useful in the treatment of prostatic carcinoma and is capable of inhibiting prostatic nuclear uptake of androgen.
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TLDR
A method was developed for the semiquantitative assessment of body hair growth, and suitable for use in the study of clinical problems associated with hirsuties in women, and an “hormonal” score obtained by adding the gradings obtained from 9 of the 11 sites is being employed in clinical studies.
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TLDR
This study demonstrates that flutamide produces multiple functional, reversible, cirrhosis-like disturbances of steroid metabolism, which are universal in the patients studied regardless of whether they had clinical responses toFlutamide, and doubts that the steroid metabolic changes play a role in the therapeutic effect of the drug.
Experience with flutamide in patients with advanced prostatic cancer without prior endocrine therapy
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Flutamide appears to be a safe antiandrogen, usually effective in the management of patients with advanced prostatic cancer who have had no prior endocrine therapy.
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A comparative study in castrated rats revealed that Sch 13521 was equipotent to cyproterone acetate (CPA) as an antiandrogen, but unlike CPA, it did not effect parturition time.
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