Flupirtine in Pain Management

@article{Devulder2010FlupirtineIP,
  title={Flupirtine in Pain Management},
  author={Jacques Devulder},
  journal={CNS Drugs},
  year={2010},
  volume={24},
  pages={867-881}
}
  • J. Devulder
  • Published 1 October 2010
  • Biology, Medicine
  • CNS Drugs
Flupirtine is a centrally acting, non-opioid analgesic that is available in a number of European countries for the treatment of a variety of pain states. The therapeutic benefits seen with flupirtine relate to its unique pharmacological properties. Flupirtine displays indirect NDMA receptor antagonism via activation of potassium channels and is the first representative of a pharmacological class denoted the ‘selective neuronal potassium channel openers’. The generation of the M-current is… 

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