Flupirtine: pharmacology and clinical applications of a nonopioid analgesic and potentially neuroprotective compound

  title={Flupirtine: pharmacology and clinical applications of a nonopioid analgesic and potentially neuroprotective compound},
  author={C. Klawe and M. Maschke},
  journal={Expert Opinion on Pharmacotherapy},
  pages={1495 - 1500}
  • C. Klawe, M. Maschke
  • Published 2009
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • Background: Flupirtine is a nonopioid drug without antipyretic or antiphlogistic properties and with a favorable tolerability. It constitutes a unique class within the group of nonsteroidal analgesics and displays a peculiar pharmacodynamic profile that invites the investigation of applications beyond the pain-relieving effect. Objective: This review describes and evaluates the pharmacologic and clinical literature regarding flupirtine and discusses its future potential. Methods: A search of… CONTINUE READING
    Flupirtine is a safe alternative drug in patients with hypersensitivity to NSAIDs
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    Pharmacokinetic profiles of the analgesic drug flupirtine in cats.
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    Flupirtine: A Human Drug with Potential for Use in the Veterinary Field
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    Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1.
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