Flupenthixol and cefotiam: effects on vitamin A metabolism in rats

@article{Schindler2004FlupenthixolAC,
  title={Flupenthixol and cefotiam: effects on vitamin A metabolism in rats},
  author={R. Schindler and Tanja Fielenbach and G. Rave},
  journal={British Journal of Nutrition},
  year={2004},
  volume={92},
  pages={597 - 605}
}
We examined the alterations in vitamin A metabolism as a result of flupenthixol or cefotiam administration. The impact of these drugs on indices of vitamin A status was evaluated in Brown Norway and Long–Evans rats. Intramuscular drug administration for 28 d resulted in a decline in systemic retinol. Changes in circulating retinol with time for chronic dosing showed drug treatment (P<0·001) and time (P<0·03) to be significant factors, but rat strain (P=0·33) was not a significant factor… Expand
5 Citations
Effect of cis-(Z)-flupentixol on DPPC membranes in the presence and absence of cholesterol.
  • 5
Retinoid-xenobiotic interactions: the Ying and the Yang.
  • 13

References

SHOWING 1-10 OF 54 REFERENCES
Vitamin A metabolism is altered in brown Norway and long-Evans rats infused with naftidrofuryl or erythromycin intravenously.
  • 2
Strain variation in vitamin A (retinol) status of streptozotocin-induced diabetic rats.
  • P. Tuitoek, J. Lakey, R. Rajotte, T. Basu
  • Medicine
  • International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
  • 1996
  • 7
Bioavailability of vitamin A in the rat following ingestion of neomycin sulfate or aluminium hydroxide.
  • R. M. Fávaro, H. C. Silva, H. Vannucchi
  • Chemistry, Medicine
  • International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
  • 1994
  • 3
Decreased hepatic vitamin A after drug administration in men and in rats.
  • 60
  • Highly Influential
Cyclosporine administration decreases liver vitamin A stores in normal and vitamin A-deficient rats.
  • 7
Serum Cholesterol Reduction by Para-Aminosalicylates in Man. 1–131 Triolein Absorption Studies.∗
  • P. Samuel, H. Price, O. B. Shalchi
  • Medicine
  • Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1965
  • 6
Clinical Pharmacokinetics of Cefotiam
  • 17
Secretion of vitamin A and retinol-binding protein into plasma is depressed in rats by N-(4-hydroxyphenyl)retinamide (fenretinide).
  • 19
EFFECT OF NEOMYCIN AND KANAMYCIN UPON INTESTINAL ABSORPTION *
  • 59
Differences in hepatic drug accumulation and enzyme induction after chronic amiodarone feeding of two rat strains: role of the hydroxylator phenotype?
  • 10
...
1
2
3
4
5
...