Fluoxetine tenth anniversary update: the progress continues.

  title={Fluoxetine tenth anniversary update: the progress continues.},
  author={Peter E. Stokes and Anders Holtz},
  journal={Clinical therapeutics},
  volume={19 5},
This tenth anniversary review/update of fluoxetine concentrates on the past 5 years of its clinical application. The mechanism of action of fluoxetine; its metabolism; its efficacy in patients with various diagnostic subgroups of depression, patients with coincident medical disease, children and adolescents with depression, patients with eating disorders, and patients with obsessive-compulsive disorder (OCD); its long-term (maintenance) efficacy; its side effects and toxicity; and… CONTINUE READING