Fluoxetine reverses stress-induced fimbria-prefrontal long-term potentiation facilitation.

@article{Kessal2006FluoxetineRS,
  title={Fluoxetine reverses stress-induced fimbria-prefrontal long-term potentiation facilitation.},
  author={Karima Kessal and Olivier Deschaux and Aline Chessel and Lin Huao Xu and J. V. Moreau and Rene Henriquez Garcia},
  journal={Neuroreport},
  year={2006},
  volume={17 3},
  pages={319-22}
}
Stress has been reported to disrupt the induction of synaptic plasticity in different fimbria target structures. The aim of the present study was to investigate whether chronic mild stress may also affect synaptic plasticity in the medial prefrontal cortex, a fimbria target structure. Fimbria tetanus (100 Hz) did not produce any changes in medial prefrontal cortex synaptic efficacy in non-stressed rats. Rats exposed to chronic mild stress, however, developed significant long-term potentiation… CONTINUE READING