Fluoxetine-induced decrements in sexual responses of female rats and hamsters are reversed by 3α,5α-THP.


INTRODUCTION Sexual dysfunction, as a result of selective-serotonin reuptake inhibitor (SSRI) treatment among women, is relatively common and is a factor in medication compliance. The mechanisms that underlie these side-effects of SSRIs are not well-understood. SSRIs can alter activity of catabolic enzymes that are involved in progesterone's conversion to 5… (More)
DOI: 10.1111/j.1743-6109.2010.01814.x