Fluoxetine in major depression: efficacy, safety and effects on sleep polygraphic variables.

@article{Kerkhofs1990FluoxetineIM,
  title={Fluoxetine in major depression: efficacy, safety and effects on sleep polygraphic variables.},
  author={Myriam Kerkhofs and C. Rielaert and Viviane de Maertelaer and Paul Linkowski and M. Czarka and Julien Mendlewicz},
  journal={International clinical psychopharmacology},
  year={1990},
  volume={5 4},
  pages={253-60}
}
Fluoxetine (60 mg), a selective inhibitor of the reuptake of 5-HT, was compared in a double-blind trial to amitriptyline (150 mg) in a sample of 34 patients fitting the Research Diagnostic Criteria for a major depressive disorder. Patients were studied after a drug washout period of 10 days and an active treatment period of 42 days. Sleep polygraphic recordings were performed before and at the end of the study. As indicated by the significant decrease in the Hamilton Depression scale and the… CONTINUE READING

From This Paper

Topics from this paper.
8 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…