Fluoxetine for acute treatment of depression in children and adolescents: a placebo-controlled, randomized clinical trial.

@article{Emslie2002FluoxetineFA,
  title={Fluoxetine for acute treatment of depression in children and adolescents: a placebo-controlled, randomized clinical trial.},
  author={Graham J. Emslie and John Harrison Heiligenstein and Karen Dineen Wagner and Sharon L. Hoog and Daniel E Ernest and Eileen B. Brown and Mary E. Nilsson and Jennie G Jacobson},
  journal={Journal of the American Academy of Child and Adolescent Psychiatry},
  year={2002},
  volume={41 10},
  pages={
          1205-15
        }
}
BACKGROUND This report presents results from the acute treatment phase of a clinical trial designed to confirm efficacy of a fixed dose of 20 mg of fluoxetine in children and adolescents with major depressive disorder (MDD). METHOD After a 3-week screening period, 122 children and 97 adolescents with MDD ( ) were randomly assigned to placebo or fluoxetine. After a 1-week placebo lead-in, fluoxetine-treated patients received fluoxetine 10 mg/day for 1 week, then fluoxetine 20 mg/day for 8… CONTINUE READING

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