Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus

@article{Jin2009FluoxetineAK,
  title={Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus},
  author={Yinchuan Jin and C Lim and Seung-Woo Kim and Ju-Young Park and Ja-Kyeong Lee},
  journal={Brain Research},
  year={2009},
  volume={1281},
  pages={108-116}
}
Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) and one of the commonly prescribed antidepressants. Numerous clinical observations and animal studies indicate that fluoxetine enhances the anticonvulsant potencies of several antiepileptic drugs. In the previous report, we showed that fluoxetine strongly protects against delayed cerebral ischemic injury. In the present study, the authors investigated whether fluoxetine has a beneficial effect on KA-induced neuronal cell death. An… CONTINUE READING

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