Fluoxetine and WAY 100,635 dissociate increases in scototaxis and analgesia induced by conspecific alarm substance in zebrafish (Danio rerio Hamilton 1822)

@article{Maximino2014FluoxetineAW,
  title={Fluoxetine and WAY 100,635 dissociate increases in scototaxis and analgesia induced by conspecific alarm substance in zebrafish (Danio rerio Hamilton 1822)},
  author={Caio Maximino and M{\^o}nica Angelim Gomes de Lima and Carina Cardoso Costa and I{\^e}da Maria Louzada Guedes and Anderson Manoel Herculano},
  journal={Pharmacology Biochemistry and Behavior},
  year={2014},
  volume={124},
  pages={425-433}
}
Alarm reactions to a substance secreted by the damaged skin of conspecifics and closely-related species are increasingly being recognized as fear-like responses in fish. The neurochemical underpinnings of these effects are so far unknown; however, given the role of the serotonergic system on defensive behavior, it is possible that the alarm reaction is mediated by this monoamine. Exposure to conspecific alarm substance (CAS) increased anxiety-like behavior in the light/dark test in zebrafish… CONTINUE READING