Fluoxetine and Oculomotor Activity during Sleep in Depressed Patients

@article{Armitage1995FluoxetineAO,
  title={Fluoxetine and Oculomotor Activity during Sleep in Depressed Patients},
  author={Roseanne Armitage and Madhukar H. Trivedi and John A. Rush},
  journal={Neuropsychopharmacology},
  year={1995},
  volume={12},
  pages={159-165}
}
The effects of fluoxetine on automated measures of electrooculographic (EOG) and electromyographic (EMG) activity were evaluated in 41 patients with nonpsychotic, major depressive disorder. Sleep EEG evaluations were conducted at baseline, while patients were symptomatic and unmedicated, and following four to five weeks of treatment with fluoxetine (20 mg). The number of eye movements (> 75 μV) and the amplitude of EOG and EMG activity increased significantly on treatment in REM, stages 1, 2… CONTINUE READING

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