Fluoxetine and Oculomotor Activity during Sleep in Depressed Patients

  title={Fluoxetine and Oculomotor Activity during Sleep in Depressed Patients},
  author={Roseanne Armitage and Madhukar H. Trivedi and John A. Rush},
The effects of fluoxetine on automated measures of electrooculographic (EOG) and electromyographic (EMG) activity were evaluated in 41 patients with nonpsychotic, major depressive disorder. Sleep EEG evaluations were conducted at baseline, while patients were symptomatic and unmedicated, and following four to five weeks of treatment with fluoxetine (20 mg). The number of eye movements (> 75 μV) and the amplitude of EOG and EMG activity increased significantly on treatment in REM, stages 1, 2… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 14 extracted citations

Antidepressant medications, neuroleptics, and prominent eye movements during NREM sleep.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society • 2009
View 3 Excerpts

Computer-assisted method for quantifying sleep eye movements that reflects medication effects

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society • 2009

Similar Papers

Loading similar papers…