Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex

@article{Bymaster2001FluoxetineBN,
  title={Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex},
  author={Frank P. Bymaster and Wei Zhang and Petra A. Carter and Janice Shaw and Eyassu Chernet and Lee Phebus and David T. Wong and Kenneth Perry},
  journal={Psychopharmacology},
  year={2001},
  volume={160},
  pages={353-361}
}
Rationale: The selective serotonin uptake inhibitor (SSRI) fluoxetine has been shown to not only increase the extracellular concentrations of serotonin, but also dopamine and norepinephrine extracellular concentrations in rat prefrontal cortex. The effect of other SSRIs on monoamine concentrations in prefrontal cortex has not been thoroughly studied. Objective: The aim of this study was to compare the ability of five systemically administered selective serotonin uptake inhibitors to increase… CONTINUE READING
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Effect of a selective 5 - hydroxytryptamine reuptake inhibitor on brain extracellular noradrenaline : microdialysis studies using paroxetine

  • E Hajos-Korcsok, McTavish SFB, T Sharp
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