Fluoroquinolones, tuberculosis, and resistance.

@article{Ginsburg2003FluoroquinolonesTA,
  title={Fluoroquinolones, tuberculosis, and resistance.},
  author={Amy Sarah Ginsburg and Jacques H. Grosset and William R Bishai},
  journal={The Lancet. Infectious diseases},
  year={2003},
  volume={3 7},
  pages={432-42}
}
Although the fluoroquinolones are presently used to treat tuberculosis primarily in cases involving resistance or intolerance to first-line antituberculosis therapy, these drugs are potential first-line agents and are under study for this indication. However, there is concern about the development of fluoroquinolone resistance in Mycobacterium tuberculosis, particularly when administered as monotherapy or as the only active agent in a failing multidrug regimen. Treatment failures as well as… CONTINUE READING
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