Fluoroquinolone therapy for bloodstream infections caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae.

@article{Lo2017FluoroquinoloneTF,
  title={Fluoroquinolone therapy for bloodstream infections caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae.},
  author={Ching-Lung Lo and Ching-Chih Lee and Chia-Wen Li and Ming-Chi Li and Po Ren Hsueh and N A Lee and Wen-Chien Ko},
  journal={Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi},
  year={2017},
  volume={50 3},
  pages={355-361}
}
BACKGROUND/PURPOSE For extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae infections, carbapenems are recommended as first line therapy, and clinical data on the therapeutic efficacy of fluoroquinolones (FQs) is limited. This study compares the efficacy of FQs and carbapenems for bloodstream infections caused by ESBL-producing Escherichia coli or Klebsiella pneumoniae. METHODS Between 2008 and 2010, adults with ESBL-producing E. coli or K. pneumoniae bacteremia at two… CONTINUE READING

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