Fluoroquinolone resistance in patients with newly diagnosed tuberculosis.

@article{Ginsburg2003FluoroquinoloneRI,
  title={Fluoroquinolone resistance in patients with newly diagnosed tuberculosis.},
  author={Amy Sarah Ginsburg and Nancy Hooper and Nikki Parrish and Kelly E Dooley and Susan E. Dorman and Jay Booth and Marie Diener-West and William G. Merz and William R Bishai and Timothy R. Sterling},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2003},
  volume={37 11},
  pages={1448-52}
}
Fluoroquinolones are widely used for the treatment of bacterial infections and are also second-line therapy for tuberculosis. However, fluoroquinolone resistance in patients with newly diagnosed cases of tuberculosis is not routinely assessed. We performed in vitro susceptibility testing of Mycobacterium tuberculosis to fluoroquinolones for all culture-confirmed tuberculosis cases in adults that were diagnosed at Johns Hopkins Hospital (Baltimore) between January 1998 and March 2002. Fifty-five… CONTINUE READING
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