Fluoroquinolone-induced liver injury: three new cases and a review of the literature

  title={Fluoroquinolone-induced liver injury: three new cases and a review of the literature},
  author={Anna Licata and Claudia Randazzo and Ilaria Morreale and Giuseppe Butera and Natale D’Alessandro and Antonio Crax{\`i}},
  journal={European Journal of Clinical Pharmacology},
Fluoroquinolones are popular and widely used in primary care and hospital settings. Premarketing studies showed a favourable side-effect profile. However, significant morbidity and the need for liver transplantation for acute liver failure have been reported. We reviewed the available data on liver damage linked to fluoroquinolones. A systematic search of case reports on the MEDLINE database encompassing the years 2000–2011 was carried out. Additional references were found by a manual search of… CONTINUE READING
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