Fluoroquinolone AUIC break points and the link to bacterial killing rates. Part 2: human trials.

@article{Schentag2003FluoroquinoloneAB,
  title={Fluoroquinolone AUIC break points and the link to bacterial killing rates. Part 2: human trials.},
  author={Jerome J. Schentag and Alison K Meagher and Alan Forrest},
  journal={The Annals of pharmacotherapy},
  year={2003},
  volume={37 10},
  pages={1478-88}
}
OBJECTIVE To review clinical trials with fluoroquinolones and the pharmacokinetic and pharmacodynamic parameters predictive of clinical and microbiologic outcomes and resistance. Data on fluoroquinolones are summarized and the premise that a single AUIC target >125 may be used for all fluoroquinolones against all target organisms is examined. DATA SOURCES Primary articles were identified by a MEDLINE search (1966-February 2002) and through secondary sources. STUDY SELECTION AND DATA… CONTINUE READING

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