Fluorometric assay for N-acetylprocainamide.

@article{Matusik1975FluorometricAF,
  title={Fluorometric assay for N-acetylprocainamide.},
  author={E. Matusik and T. Gibson},
  journal={Clinical chemistry},
  year={1975},
  volume={21 13},
  pages={
          1899-902
        }
}
  • E. Matusik, T. Gibson
  • Published 1975
  • Medicine, Chemistry
  • Clinical chemistry
  • We describe a simple, rapid fluorometric assay for separate quantitative analysis of procainamide and N-acetylprocainamide in mixtures. The effective lenear range (fluorescence vs. concentration) in serum is 0.1 to 10.0 mg/liter, regardless of the ratio (by weight) of the two drugs from 1:10 to 10:1. Analytical recoveries by the extraction method used were 100.0 +/- 3.0% and 98.0 +/- 4.0%, respectively. For determination of either compound, the maximum coefficient of variation was 10%. 

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