Fluorine--a new element in the design of membrane-active peptides.

@article{Marsh2009FluorineaNE,
  title={Fluorine--a new element in the design of membrane-active peptides.},
  author={E Neil G Marsh and Benjamin C. Buer and Ayyalusamy Ramamoorthy},
  journal={Molecular bioSystems},
  year={2009},
  volume={5 10},
  pages={1143-7}
}
Antimicrobial peptides (also known as genetically encoded peptide antibiotics) are a diverse class of short cationic amphipathic polypeptides that exhibit a broad-spectrum of antimicrobial activities by selectively disrupting the bacterial cell membrane. In this review article, we present the use of fluorinated amino acids in the design of antimicrobial… CONTINUE READING