Fluorinated proteins: from design and synthesis to structure and stability.

Abstract

Fluorine is all but absent from biology; however, it has proved to be a remarkably useful element with which to modulate the activity of biological molecules and to study their mechanism of action. Our laboratory's interest in incorporating fluorine into proteins was stimulated by the unusual physicochemical properties exhibited by perfluorinated small… (More)
DOI: 10.1021/ar500125m

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