Fluorinated EuII-based multimodal contrast agent for temperature- and redox-responsive magnetic resonance imaging† †Electronic supplementary information (ESI) available. CCDC 1562330 and 1562331. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc03142d

@inproceedings{Basal2017FluorinatedEM,
  title={Fluorinated EuII-based multimodal contrast agent for temperature- and redox-responsive magnetic resonance imaging†
†Electronic supplementary information (ESI) available. CCDC 1562330 and 1562331. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc03142d
},
  author={Lina A Basal and Matthew D. Bailey and Jonathan Camacho Romero and Meser M. Ali and Lyazat Kurenbekova and Jason T. Yustein and Robia G. Pautler and Matthew J Allen},
  booktitle={Chemical science},
  year={2017}
}
Magnetic resonance imaging (MRI) using redox-active, EuII-containing complexes is one of the most promising techniques for noninvasively imaging hypoxia in vivo. In this technique, positive (T1-weighted) contrast enhancement persists in areas of relatively low oxidizing ability, such as hypoxic tissue. Herein, we describe a fluorinated, EuII-containing complex in which the redox-active metal is caged by intramolecular interactions. The position of the fluorine atoms enables temperature… CONTINUE READING
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