Fluorinase-coupled base swaps: synthesis of [18F]-5'-deoxy-5'-fluorouridines.

Abstract

The application of positron emission tomography (PET) for medical imaging and diagnostics is a rapidly growing area, and cyclotrons are being increasingly commissioned in major hospitals. Developing methods for the introduction of the appropriate isotopes (C, N, F, and O) into organic structural motifs is a major research activity at present. The relatively… (More)
DOI: 10.1002/anie.200804040

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