Fluorimetric determination of aminoglycoside antibiotics using lanthanide probe ion spectroscopy.

The application of probe ion fluorimetry has succeeded in the microdetermination of six aminoglycoside antibiotics: neomycin, streptomycin, gentamicin, tobramycin, amikacin and kanamycin as sulfate salts in pure form and in some pharmaceutical preparations. The method is based on the reaction of Eu(3+) ions with aminoglycosides through amino and hydroxy… CONTINUE READING