Fluoride tissue distribution: short-term kinetics.

The short-term distribution kinetics of 18F, with and without added carrier, were studied in 12 soft tissues and femur following intravenous administration in rats. The animals were killed in groups of four at 5, 10, 15, 20, 30, and 60 min after the dose. A tissue was judged to be kinetically homogeneous with plasma if an early and constant tissue water-to… CONTINUE READING