Fluoride pharmacokinetics and changes in lumbar spine and hip bone mineral density.

@article{Patel1996FluoridePA,
  title={Fluoride pharmacokinetics and changes in lumbar spine and hip bone mineral density.},
  author={S. Patel and J. K. Chan and D. Hosking},
  journal={Bone},
  year={1996},
  volume={19 6},
  pages={
          651-5
        }
}
Debate about the use of fluoride for the treatment of vertebral osteoporosis has centered not only on whether fluoride treatment decreases vertebral fractures, but also the interindividual vertebral bone mineral density (BMD) response, the potential for nonvertebral fractures, as well as side effects and tolerability. These effects may be dose dependent and, in this study, we examine the pharmacokinetics of sodium monofluorophosphate (MFP) in osteoporotic patients and relate this to changes in… Expand

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