Fluoride effects on bone formation and mineralization are influenced by genetics.

Abstract

INTRODUCTION A variation in bone response to fluoride (F(-)) exposure has been attributed to genetic factors. Increasing fluoride doses (0 ppm, 25 ppm, 50 ppm, 100 ppm) for three inbred mouse strains with different susceptibilities to developing dental enamel fluorosis (A/J, a "susceptible" strain; SWR/J, an "intermediate" strain; 129P3/J, a "resistant… (More)
DOI: 10.1016/j.bone.2008.07.248

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