Fluoride Affects Calcium Homeostasis and Osteogenic Transcription Factor Expressions Through L-type Calcium Channels in Osteoblast Cell Line

@article{Duan2014FluorideAC,
  title={Fluoride Affects Calcium Homeostasis and Osteogenic Transcription Factor Expressions Through L-type Calcium Channels in Osteoblast Cell Line},
  author={Xiao-qin Duan and Zhi-tao Zhao and X. Zhang and Y. Wang and Huan Wang and Da-wei Liu and G. Li and L. Jing},
  journal={Biological Trace Element Research},
  year={2014},
  volume={162},
  pages={219-226}
}
  • Xiao-qin Duan, Zhi-tao Zhao, +5 authors L. Jing
  • Published 2014
  • Chemistry, Medicine
  • Biological Trace Element Research
  • Osteoblast L-type voltage-dependent calcium channels (VDCC) play important roles in maintaining intracellular homeostasis and influencing multiple cellular processes. In particular, they contribute to the activities and functions of osteoblasts (OBs). In order to study how L-type VDCC modulate calcium ion (Ca2+) homeostasis and the expression of osteogenic transcription factors in OBs exposed to fluoride, MC3T3-E1 cells were exposed to a gradient of concentrations of fluoride (0, 2.0, 5.0, 10.0… CONTINUE READING
    12 Citations
    Mechanisms of Intracellular Calcium Homeostasis in MC3T3-E1 Cells and Bone Tissues of Sprague-Dawley Rats Exposed to Fluoride
    • 4
    Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells
    • 5
    Effect of fluoride exposure on mRNA expression of cav1.2 and calcium signal pathway apoptosis regulators in PC12 cells.
    • 7
    Fluoride Affects Calcium Homeostasis by Regulating Parathyroid Hormone, PTH-Related Peptide, and Calcium-Sensing Receptor Expression
    • 8
    ClC‐3 Promotes Osteogenic Differentiation in MC3T3‐E1 Cell After Dynamic Compression
    • 9

    References

    SHOWING 1-10 OF 57 REFERENCES
    Role of Unfolded Protein Response in Affecting Osteoblast Differentiation Induced by Fluoride
    • 12
    Rodent Osteoblastic Cells Express Voltage-Sensitive Calcium Channels Lacking a γ Subunit
    • 17
    Rodent osteoblastic cells express voltage-sensitive calcium channels lacking a gamma subunit.
    • 8
    Calcium signals and calcium channels in osteoblastic cells.
    • 127
    Role of Oxidative Stress in Osteoblasts Exposed to Sodium Fluoride
    • 25