Fluorescentin situ hybridization assessment of chromosome 8 copy number in breast cancer

Abstract

Conventional cytogenetics of breast and other solid tumors has been hampered by a number of factors. An analysis of breast tumor tissues was therefore undertaken using fluorescentin situ hybridization (FISH). A total of 34 specimens were analyzed using a chromosome 8-specific α-satellite probe. Various approaches were tested and compared. Among 30… (More)
DOI: 10.1007/BF01806674

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