Fluorescent stilbazolium dyes as probes of the norepinephrine transporter: structural insights into substrate binding.

Abstract

We report the synthesis, binding kinetics, optical spectroscopy and predicted binding modes of a series of sterically demanding, fluorescent norepinephrine transporter (NET) ligands. A series of bulky stilbazolium dyes, including six newly synthesized compounds, were evaluated to determine the effect of extending the molecular probes' 'heads' or 'tails… (More)
DOI: 10.1039/c2ob26633d

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@article{Wilson2012FluorescentSD, title={Fluorescent stilbazolium dyes as probes of the norepinephrine transporter: structural insights into substrate binding.}, author={James N Wilson and Adrienne S Brown and W. Michael Babinchak and Clark D Ridge and Jamie Dale Walls}, journal={Organic & biomolecular chemistry}, year={2012}, volume={10 43}, pages={8710-9} }