Fluorescent probes for opioid receptors.

Abstract

Naloxone, naltrexone and oxymorphone were labeled in position 6 with fluorescein by coupling their hydrazone analogs with fluorescein isothiocyanate. Naloxone was also coupled in a similar way with rhodamine-B. The compounds thus obtained were: "6-FN", [1-(N)-fluoresceinyl naloxone thiosemicarbazone]; "6-FNX", [1-(N)-fluoresceinyl naltrexone… (More)

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@article{Kolb1983FluorescentPF, title={Fluorescent probes for opioid receptors.}, author={Vera M. Kolb and Ahmet Department of Pharmaceutical Pharmacology Koman and Lars Terenius}, journal={Life sciences}, year={1983}, volume={33 Suppl 1}, pages={423-6} }