Fluorescent in situ hybridization diagnosis of extramedullary nodal blast crisis.

Abstract

The t(9;22)(q34;q11) translocation between bcr and abl genes plays a pivotal role in the pathogenesis and diagnosis of chronic myelogenous leukemia (CML). Fluorescence in situ hybridization (FISH) using specific DNA probes provides a useful and accurate way for the detection of bcr/abl fusion gene in single cell. Here, we report an unusual case of a patient… (More)
DOI: 10.1002/dc.21795

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